Green Clean is a concentrated, a 2oz bottle will make 1 to 4 gallons of solution and can be used during any stage of development through harvest without the use of any kind of protective gear. No suiting up to spray. Shake Green Clean REALLY WELL before measuring and again after adding to water! Shake every few minutes while spraying. Do not spray late flowering plants in their last couple weeks before harvest at a heavy mix more than a time or two. Better to spray a lite mix and to spray more often. Green Clean will kill every mite you can spray it on, but you can't spray Green Clean on the inner flower, but you can keep them under control. With spider mites, you need to kill them before flowering or in early flowering. Every plant brought into grow room should be quarantined and deemed clean before entering. It's really important that Green Clean gets mixed well before measuring to make the spray. When adding to water, mix again, and shake spray device every few minutes to keep it mixed. We use a pressurised pump type sprayer set to the finest spray possible. It's also important to spray without main lights on in the grow room. Let plants dry well before lights are turned back on. Spray in early morning outdoors.